Smarting from a 5-3 loss to Clemson, Blue Devil hitters rapped out 14 hits including three home runs. Ryan Deitrich hit a solo homer in the fourth to start the scoring. Andy Perez followed with a solo homer of his own in the fifth. A two-run shot by Jordan Betts opened the lead to 4-0 in the seventh.
The Devils added single insurance runs in the eighth and ninth innings.
Duke starter Drew Van Orden went the distance giving up just five hits and striking out eight.
The No. 4 seed Devils, 1-1 in the tournament, get Friday off before continuing round-robin play Saturday at 11 am against top-seed Miami.